{"markup":"\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\n    \u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022\n    xmlns:content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022\n    xmlns:dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022\n    xmlns:foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022\n    xmlns:og=\u0022http:\/\/ogp.me\/ns#\u0022\n    xmlns:rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022\n    xmlns:sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022\n    xmlns:sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022\n    xmlns:skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022\n    xmlns:xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022\n    xmlns:mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\n  \u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/d282kpwvnogo5m.cloudfront.net\/sites\/default\/files\/js\/js_itu2PgFdrjV-docKmLK8Jn5oXe_05RgvQh73eOhI_mE.js\u0022\u003E\u003C\/script\u003E\n\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/mdc.sagepub.com\/sites\/all\/modules\/highwire\/highwire\/plugins\/highwire_markup_process\/js\/highwire_at_symbol.js?nzlfg2\u0022\u003E\u003C\/script\u003E\n\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/mdc.sagepub.com\/sites\/all\/modules\/highwire\/highwire\/plugins\/highwire_markup_process\/js\/highwire_article_reference_popup.js?nzlfg2\u0022\u003E\u003C\/script\u003E\n\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/d282kpwvnogo5m.cloudfront.net\/sites\/default\/files\/js\/js_I8yX6RYPZb7AtMcDUA3QKDZqVkvEn35ED11_1i7vVpc.js\u0022\u003E\u003C\/script\u003E\n\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\n(function(i,s,o,g,r,a,m){i[\u0022GoogleAnalyticsObject\u0022]=r;i[r]=i[r]||function(){(i[r].q=i[r].q||[]).push(arguments)},i[r].l=1*new Date();a=s.createElement(o),m=s.getElementsByTagName(o)[0];a.async=1;a.src=g;m.parentNode.insertBefore(a,m)})(window,document,\u0022script\u0022,\u0022\/\/www.google-analytics.com\/analytics.js\u0022,\u0022ga\u0022);ga(\u0022create\u0022, \u0022UA-15605596-27\u0022, {\u0022cookieDomain\u0022:\u0022auto\u0022});ga(\u0022set\u0022, \u0022page\u0022, location.pathname + location.search + location.hash);ga(\u0022send\u0022, \u0022pageview\u0022);ga(\u0027create\u0027, \u0027UA-189672-26\u0027, \u0027auto\u0027, {\u0027name\u0027: \u0027hwTracker\u0027});\r\nga(\u0027hwTracker.send\u0027, \u0027pageview\u0027);\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\n\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022highwire\u0022:{\u0022markup\u0022:[{\u0022requested\u0022:\u0022full-text\u0022,\u0022variant\u0022:\u0022full-text\u0022,\u0022view\u0022:\u0022full\u0022,\u0022pisa\u0022:\u0022spmdc;15\\\/28_suppl_1\\\/ii\u0022},{\u0022requested\u0022:\u0022long\u0022,\u0022variant\u0022:\u0022full-text\u0022,\u0022view\u0022:\u0022full\u0022,\u0022pisa\u0022:\u0022spmdc;15\\\/28_suppl_1\\\/ii\u0022}],\u0022ac\u0022:{\u0022spmdc;15\\\/28_suppl_1\\\/ii\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022full\u0022:true},\u0022pisa_id\u0022:\u0022spmdc;15\\\/28_suppl_1\\\/ii\u0022,\u0022atom_uri\u0022:\u0022\u0022,\u0022jcode\u0022:\u0022spmdc\u0022}}},\u0022googleanalytics\u0022:{\u0022trackOutbound\u0022:1,\u0022trackMailto\u0022:1,\u0022trackDownload\u0022:1,\u0022trackDownloadExtensions\u0022:\u00227z|aac|arc|arj|asf|asx|avi|bin|csv|doc(x|m)?|dot(x|m)?|exe|flv|gif|gz|gzip|hqx|jar|jpe?g|js|mp(2|3|4|e?g)|mov(ie)?|msi|msp|pdf|phps|png|ppt(x|m)?|pot(x|m)?|pps(x|m)?|ppam|sld(x|m)?|thmx|qtm?|ra(m|r)?|sea|sit|tar|tgz|torrent|txt|wav|wma|wmv|wpd|xls(x|m|b)?|xlt(x|m)|xlam|xml|z|zip\u0022,\u0022trackUrlFragments\u0022:1},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u0022sites\\\/all\\\/libraries\\\/cluetip\\\/jquery.cluetip.js\u0022:1,\u0022sites\\\/all\\\/libraries\\\/cluetip\\\/lib\\\/jquery.hoverIntent.js\u0022:1,\u0022sites\\\/all\\\/libraries\\\/cluetip\\\/lib\\\/jquery.bgiframe.min.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/highwire_markup_process\\\/js\\\/highwire_at_symbol.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/highwire_markup_process\\\/js\\\/highwire_article_reference_popup.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/google_analytics\\\/googleanalytics.js\u0022:1,\u00220\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\n\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/d282kpwvnogo5m.cloudfront.net\/sites\/default\/files\/advagg_css\/css__ce2QY63WIanKyr8eSq7eavr1XQRRmFD6ZSmwpyJi8lM__zXwFqpqmxrZOXXcd_TpBQpjuELbmIP9wBR5UuTDWAO4__YJWWMMdfCJuAFm5cUEp88OsodhO3ZA-2lzRfoBsSlk4.css\u0022 media=\u0022all\u0022 \/\u003E\n\u003Clink rel=\u0027stylesheet\u0027 type=\u0027text\/css\u0027 href=\u0027\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0027 \/\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-sageoa-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022 \u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-markup\u0022 \u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022highwire-markup\u0022\u003E\u003Cdiv xmlns=\u0022http:\/\/www.w3.org\/1999\/xhtml\u0022 id=\u0022content-block-markup\u0022 xmlns:xhtml=\u0022http:\/\/www.w3.org\/1999\/xhtml\u0022\u003E\u003Cdiv class=\u0022article fulltext-view \u0022\u003E\u003Cspan class=\u0022highwire-journal-article-marker-start\u0022\u003E\u003C\/span\u003E\u003Cul class=\u0022kwd-group\u0022\u003E\u003Cli class=\u0022kwd\u0022\u003E\u003C\/li\u003E\u003C\/ul\u003E\u003Cdiv class=\u0022section\u0022 id=\u0022sec-1\u0022\u003E\u003Cp id=\u0022p-1\u0022\u003EDear Practitioner,\u003C\/p\u003E\u003Cp id=\u0022p-2\u0022\u003EWe are pleased to share with you this special issue with a focus on cardiovascular disease (CVD) prevention from presentations at the European Society of Cardiology Congress 2015 held in London, United Kingdom.\u003C\/p\u003E\u003Cp id=\u0022p-3\u0022\u003ECVD is the leading cause of death and a major cause of disability worldwide, highlighting a need for increased public awareness with particular focus on disease prevention. The articles in this issue will provide you with information on treatment options for dyslipidemia, the role of personalized medicine in CVD prevention, and other innovations and programs aimed at improving public health by reducing the burden of heart disease.\u003C\/p\u003E\u003Cp id=\u0022p-4\u0022\u003EStatins are the most widely prescribed class of medications used to lower cholesterol, and trials have shown them to be effective in patients with CVD. They are also used extensively in patients without previously diagnosed CVD who have elevated low-density lipoprotein cholesterol levels and risk factors such as diabetes and hypertension that can increase the risk of CVD. A study featured in this issue analyzed the records of over 45\u2005000 Medicare beneficiaries and revealed that patients who adhere well to high-intensity statins or low-\/moderate-intensity statins have fewer recurrences of myocardial infarction, fewer hospitalizations due to CVD, and fewer all-cause mortalities, yet low adherence to therapy or discontinuation is common.\u003C\/p\u003E\u003Cp id=\u0022p-5\u0022\u003ESmartphone apps are increasingly being used to help motivate patients to adopt and maintain a healthy lifestyle. The SUPPORT trial studied patients with acute myocardial infarction being treated with ticagrelor, and it demonstrated the value of an interactive smartphone app in boosting drug adherence and adopting\/continuing healthy cardiovascular lifestyle changes.\u003C\/p\u003E\u003Cp id=\u0022p-6\u0022\u003EOther articles in this issue explore additional options for lipid-lowering therapy in patients for whom statins might not be the best option, recent improvements and innovations that could advance the field of CVD prevention and significantly improve public health, and goals and interventions that aim to achieve the World Heart Federation\u2019s objective to reduce premature deaths from CVD by 25% by the year 2025.\u003C\/p\u003E\u003Cp id=\u0022p-7\u0022\u003EWe hope that you find the articles and practical perspectives that are contained in the pages of this focus issue of \u003Cem\u003EESC Congress 2015 in Review\u003C\/em\u003E helpful in integrating this new information into your clinical practice. For more information, please visit \u003Ca href=\u0022http:\/\/mdce.sagepub.com\u0022\u003Emdce.sagepub.com\u003C\/a\u003E.\u003C\/p\u003E\u003C\/div\u003E\u003Cdiv class=\u0022sig-block\u0022\u003E\n\u003Cdiv class=\u0022sig\u0022\u003E\u003Cp\u003E\u003Cstrong\u003ERobert P. Giugliano, MD, SM\u003C\/strong\u003E\u003Cbr\/\u003EPhysician\u003Cbr\/\u003ECardiovascular Division\u003Cbr\/\u003EBrigham and Women\u2019s Hospital\u003Cbr\/\u003EAssociate Professor in Medicine\u003Cbr\/\u003EHarvard Medical School\u003Cbr\/\u003EBoston, MA\u003C\/p\u003E\u003C\/div\u003E\n\u003Cdiv class=\u0022sig\u0022\u003E\u003Cp\u003E\u003Cstrong\u003EMarc P. Bonaca, MD, MPH\u003C\/strong\u003E\u003Cbr\/\u003EAssociate Physician\u003Cbr\/\u003ECardiovascular Division\u003Cbr\/\u003EBrigham and Women\u2019s Hospital\u003Cbr\/\u003EInstructor in Medicine Harvard Medical School\u003Cbr\/\u003EBoston, MA\u003C\/p\u003E\u003C\/div\u003E\n\u003Cdiv class=\u0022sig\u0022\u003E\u003Cp\u003E\u003Cstrong\u003EJacob A. Udell, MD, MPH\u003C\/strong\u003E\u003Cbr\/\u003EAssociate Physician\u003Cbr\/\u003ECardiovascular Division\u003Cbr\/\u003EWomen\u2019s College Hospital\u003Cbr\/\u003EAssociate Professor of Medicine\u003Cbr\/\u003EUniversity of Toronto\u003Cbr\/\u003EToronto, Ontario, Canada\u003C\/p\u003E\u003C\/div\u003E\n\u003Cdiv class=\u0022sig\u0022\u003E\u003Cp\u003E\u003Cstrong\u003ENihar R. Desai, MD, MPH\u003C\/strong\u003E\u003Cbr\/\u003EAssociate Physician\u003Cbr\/\u003ECardiovascular Division\u003Cbr\/\u003EYale-New Haven Hospital\u003Cbr\/\u003ENew Haven, CT\u003C\/p\u003E\u003C\/div\u003E\n\u003Cdiv class=\u0022sig\u0022\u003E\u003Cp\u003E\u003Cstrong\u003EMatthew Cavender, MD, MPH\u003C\/strong\u003E\u003Cbr\/\u003ECardiovascular Division\u003Cbr\/\u003EBrigham and Women\u2019s Hospital\u003Cbr\/\u003EBoston, MA\u003C\/p\u003E\u003C\/div\u003E\n\u003Cdiv class=\u0022sig\u0022\u003E\u003Cp\u003E\u003Cstrong\u003ESameer Bansilal, MD, MS\u003C\/strong\u003E\u003Cbr\/\u003EAssistant Professor\u003Cbr\/\u003EMount Sinai Hospital\u003Cbr\/\u003EIcahn School of Medicine\u003Cbr\/\u003ENew York, NY\u003C\/p\u003E\u003C\/div\u003E\n\u003Cdiv class=\u0022sig\u0022\u003E\u003Cp\u003E\u003Cstrong\u003EErin A. Bohula May, MD, PhD\u003C\/strong\u003E\u003Cbr\/\u003EAssociate Physician\u003Cbr\/\u003ECardiovascular Division\u003Cbr\/\u003EBrigham and Women\u2019s Hospital\u003Cbr\/\u003EInstructor in Medicine\u003Cbr\/\u003EHarvard Medical School\u003Cbr\/\u003EBoston, MA\u003C\/p\u003E\u003C\/div\u003E\n\u003Cdiv class=\u0022sig\u0022\u003E\u003Cp\u003E\u003Cstrong\u003EDylan L. Steen, MD, MS\u003C\/strong\u003E\u003Cbr\/\u003EAssociate Physician\u003Cbr\/\u003ECardiovascular Division\u003Cbr\/\u003EUniversity of Cincinnati\u003Cbr\/\u003ECincinnati, OH\u003C\/p\u003E\u003C\/div\u003E\n\u003C\/div\u003E\u003Cul class=\u0022copyright-statement\u0022\u003E\u003Cli class=\u0022fn\u0022 id=\u0022copyright-statement-1\u0022\u003E\u00a9 2015 SAGE Publications\u003C\/li\u003E\u003C\/ul\u003E\u003Cspan class=\u0022highwire-journal-article-marker-end\u0022\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cspan id=\u0022related-urls\u0022\u003E\u003C\/span\u003E\u003C\/div\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/mdc.sagepub.com\/sites\/all\/modules\/highwire\/highwire\/plugins\/highwire_markup_process\/js\/highwire_openurl.js?nzlfg2\u0022\u003E\u003C\/script\u003E\n\u003C\/body\u003E\u003C\/html\u003E"}