Clinical Trial Highlights

• TL-PAS Shows Reduction of Ischemic Events with Long-Term Prasugrel
• ITALIC/ITALICplus: 12-Month Data Suggest 6 Months of DAPT is Noninferior to 24 Months of DAPT
• ISAR-SAFE: No Difference in 6-Month vs 12-Month DAPT after DES
• DAPT Study: Benefits Seen with Prolonged DAPT after DES Treatment
• Aspirin Fails to Reduce CVD in Elderly Japanese
• Alirocumab Has Greater Reduction of LDL-C Than Ezetimibe in Patients with Statin Intolerance
• Ezetimibe Plus Statin Reduces CV Events after ACS
• Losartan Lacks Benefit in Inherited HCM
• CABG Plus Valve Repair Provides No Benefit in MR over CABG Alone
• BASKET-PROVE II: BP-DES Noninferior to DP-DES
• SYNERGY Everolimus-Eluting Stent Noninferior to PROMUS Element Plus: Results from EVOLVE II Randomized Clinical Trial
• AVOID: Oxygen Use Damaging in STEMI
• PARADIGM-HF: Disease Progression Slowed with Novel Drug
• PreSERVE-AMI: CD34⁺ Cells Improve Cardiac Function, Reduce Events after STEMI
• ENGAGE AF-TIMI 48: Edoxaban Safe and Effective in Elderly Patients with AF