Clinical Trial Highlights

• Prehospital Cooling Does Not Improve Outcomes in Cardiac Arrest
• Lower-Temperature Target in Therapeutic Cooling Does Not Improve Outcomes
• Results from the ROSE AHF Study
• TOPCAT: Effects of Spironolactone on CV Outcomes in Patients with Heart Failure with Preserved Ejection Fraction
• Adverse Effects Associated with Varespladib in the VISTA-16 Trial
• Endovascular Revascularization Plus Supervised Exercise May Benefit Intermittent Claudication Patients
• EU-PACT Study: Initial Warfarin Dosing Improved by Clinical Variables and Genotype to Guide Therapy
• COAG Trial: No Advantage Seen with Genetic-Based Warfarin Dosing
• No Benefit to Renal Artery Stenting Seen in CORAL Trial
• Edoxaban Noninferior to Warfarin in the ENGAGE AF-TIMI 48 Trial
• Immediate Targeted Blood Pressure Reduction Does Not Improve Outcomes in Acute Stroke