RT Journal Article
SR Electronic
A1 Lederman, Lynne
T1 Better Molecular Profiling is Needed for Rational, Targeted Therapy in CRC
JF MD Conference Express
YR 2014
FD SAGE Publications
VO 14
IS 14
SP 22
OP 23
DO 10.1177/155989771414014
UL http://mdc.sagepub.com/content/14/14/22.abstract
AB Colorectal cancer (CRC) was one the first solid malignancies to be classified using molecular profiling, and led to the identification of critical genes and pathways involved in this disease. This article discusses future directions of biomarker research, the molecular biomarker characterization and subtyping of CRC, and the implications of tumor heterogeneity.