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- Figure 1.
Drivers of Tumor Heterogeneity in Colorectal Cancer
CIMP=CpG (cytosine-guanine dinucleotide) island methylator phenotype; CRC=colorectal cancer.
Reproduced from Loeb LA. Human cancers express mutator phenotypes: origin, consequences and targeting. Nat Rev Cancer 201111(6):450–457. With permission from the Nature Publishing Group.
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Better Molecular Profiling is Needed for Rational, Targeted Therapy in CRC
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