Summary

The IMPROVE-IT trial showed that the cholesterol-lowering drug ezetimibe, when added to simvastatin, provides greater improvement in cardiovascular outcomes among patients with diabetes vs those without diabetes in a population with acute coronary syndrome. Additionally, the rate of new-onset diabetes was not increased among patients treated with ezetimibe.

  • acute coronary syndrome
  • cardiovascular risk
  • cholesterol
  • diabetes mellitus
  • ezetimibe
  • IMPROVE-IT
  • simvastatin
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