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type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/d282kpwvnogo5m.cloudfront.net\/sites\/default\/files\/advagg_css\/css__ce2QY63WIanKyr8eSq7eavr1XQRRmFD6ZSmwpyJi8lM__zXwFqpqmxrZOXXcd_TpBQpjuELbmIP9wBR5UuTDWAO4__YJWWMMdfCJuAFm5cUEp88OsodhO3ZA-2lzRfoBsSlk4.css\u0022 media=\u0022all\u0022 \/\u003E\n\u003Clink rel=\u0027stylesheet\u0027 type=\u0027text\/css\u0027 href=\u0027\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0027 \/\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-sageoa-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022 \u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-markup\u0022 \u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022highwire-markup\u0022\u003E\u003Cdiv xmlns=\u0022http:\/\/www.w3.org\/1999\/xhtml\u0022 id=\u0022content-block-markup\u0022 xmlns:xhtml=\u0022http:\/\/www.w3.org\/1999\/xhtml\u0022\u003E\u003Cdiv class=\u0022article fulltext-view \u0022\u003E\u003Cspan class=\u0022highwire-journal-article-marker-start\u0022\u003E\u003C\/span\u003E\u003Cul class=\u0022kwd-group\u0022\u003E\u003Cli class=\u0022kwd\u0022\u003E\u003C\/li\u003E\u003C\/ul\u003E\u003Cdiv class=\u0022section\u0022 id=\u0022sec-1\u0022\u003E\u003Cp id=\u0022p-1\u0022\u003EDear Practitioner,\u003C\/p\u003E\u003Cp id=\u0022p-2\u0022\u003EWe are pleased to share with you highlights from the European Society of Cardiology (ESC) Congress 2015 held in London, United Kingdom.\u003C\/p\u003E\u003Cp id=\u0022p-3\u0022\u003EThe featured article provides a topline summary of the 5 new guidelines released by the ESC during the Congress. These guidelines cover pericardial diseases, ventricular arrhythmias and sudden cardiac death, pulmonary hypertension, infective endocarditis, and non\u2013ST segment elevation acute coronary syndromes (ACS).\u003C\/p\u003E\u003Cp id=\u0022p-4\u0022\u003ESeveral presentations on the optimal patient populations and duration for dual antiplatelet therapy (DAPT) were featured at the congress, including a meta-analysis of 6 trials that demonstrated that DAPT continued for more than 1 year among stabilized high-risk patients with previous myocardial infarction (MI), decreased the composite risk of cardiovascular (CV) death, MI, or stroke, as well as stroke and cardiovascular death alone. There was an increased risk of major bleeding in the DAPT group, but there was no significant difference in fatal bleeding or intracranial hemorrhage between the 2 groups. A new analysis of the DAPT Study revealed that cancer-related death accounted for the majority of the difference in mortality, suggesting that fatal bleeding is rare with extended DAPT and may be avoided with careful patient selection.\u003C\/p\u003E\u003Cp id=\u0022p-5\u0022\u003ESeveral other late-breaking trials are featured in this issue, including 2 new analyses of the IMPROVE-IT study. A pre-specified subgroup analysis showed that the cholesterol-lowering drug ezetimibe, when added to simvastatin, provides greater improvement in CV outcomes among patients with diabetes compared with those without diabetes in a population with ACS. The second analysis concluded that the rate of new-onset diabetes was not increased among patients treated with ezetimibe.\u003C\/p\u003E\u003Cp id=\u0022p-6\u0022\u003EIn addition to the results of the top late-breaking clinical trials, you will also find information on selected areas of cardiovascular medicine including atrial fibrillation, interventional cardiology, and the clinical challenges associated with the use of anticoagulants.\u003C\/p\u003E\u003Cp id=\u0022p-7\u0022\u003EWe hope that you find the articles and practical perspectives that are contained in the pages of this issue of \u003Cem\u003EESC Congress 2015 in Review\u003C\/em\u003E helpful in integrating this new information into your clinical practice. For more information, please visit \u003Ca href=\u0022http:\/\/mdce.sagepub.com\u0022\u003Emdce.sagepub.com\u003C\/a\u003E.\u003C\/p\u003E\u003C\/div\u003E\u003Cdiv class=\u0022sig-block\u0022\u003E\n\u003Cdiv class=\u0022sig\u0022\u003E\u003Cp\u003E\u003Cstrong\u003ERobert P. Giugliano, MD, SM\u003C\/strong\u003E\u003Cbr\/\u003EPhysician\u003Cbr\/\u003ECardiovascular Division\u003Cbr\/\u003EBrigham and Women\u2019s Hospital\u003Cbr\/\u003EAssociate Professor in Medicine\u003Cbr\/\u003EHarvard Medical School\u003Cbr\/\u003EBoston, MA\u003C\/p\u003E\u003C\/div\u003E\n\u003Cdiv class=\u0022sig\u0022\u003E\u003Cp\u003E\u003Cstrong\u003EMarc P. Bonaca, MD, MPH\u003C\/strong\u003E\u003Cbr\/\u003EAssociate Physician\u003Cbr\/\u003ECardiovascular Division\u003Cbr\/\u003EBrigham and Women\u2019s Hospital\u003Cbr\/\u003EInstructor in Medicine\u003Cbr\/\u003EHarvard Medical School\u003Cbr\/\u003EBoston, MA\u003C\/p\u003E\u003C\/div\u003E\n\u003Cdiv class=\u0022sig\u0022\u003E\u003Cp\u003E\u003Cstrong\u003EJacob A. Udell, MD, MPH\u003C\/strong\u003E\u003Cbr\/\u003EAssociate Physician\u003Cbr\/\u003ECardiovascular Division\u003Cbr\/\u003EWomen\u2019s College Hospital\u003Cbr\/\u003EAssociate Professor of Medicine\u003Cbr\/\u003EUniversity of Toronto\u003Cbr\/\u003EToronto, Ontario, Canada\u003C\/p\u003E\u003C\/div\u003E\n\u003Cdiv class=\u0022sig\u0022\u003E\u003Cp\u003E\u003Cstrong\u003ENihar R. Desai, MD, MPH\u003C\/strong\u003E\u003Cbr\/\u003EAssociate Physician\u003Cbr\/\u003ECardiovascular Division\u003Cbr\/\u003EYale-New Haven Hospital\u003Cbr\/\u003ENew Haven, CT\u003C\/p\u003E\u003C\/div\u003E\n\u003Cdiv class=\u0022sig\u0022\u003E\u003Cp\u003E\u003Cstrong\u003EMatthew Cavender, MD, MPH\u003C\/strong\u003E\u003Cbr\/\u003ECardiovascular Division\u003Cbr\/\u003EBrigham and Women\u2019s Hospital\u003Cbr\/\u003EBoston, MA\u003C\/p\u003E\u003C\/div\u003E\n\u003Cdiv class=\u0022sig\u0022\u003E\u003Cp\u003E\u003Cstrong\u003ESameer Bansilal, MD, MS\u003C\/strong\u003E\u003Cbr\/\u003EAssistant Professor\u003Cbr\/\u003EMount Sinai Hospital\u003Cbr\/\u003EIcahn School of Medicine\u003Cbr\/\u003ENew York, NY\u003C\/p\u003E\u003C\/div\u003E\n\u003Cdiv class=\u0022sig\u0022\u003E\u003Cp\u003E\u003Cstrong\u003EErin A. Bohula May, MD, PhD\u003C\/strong\u003E\u003Cbr\/\u003EAssociate Physician\u003Cbr\/\u003ECardiovascular Division\u003Cbr\/\u003EBrigham and Women\u2019s Hospital\u003Cbr\/\u003EInstructor in Medicine\u003Cbr\/\u003EHarvard Medical School\u003Cbr\/\u003EBoston, MA\u003C\/p\u003E\u003C\/div\u003E\n\u003C\/div\u003E\u003Cul class=\u0022copyright-statement\u0022\u003E\u003Cli class=\u0022fn\u0022 id=\u0022copyright-statement-1\u0022\u003E\u00a9 2015 SAGE Publications\u003C\/li\u003E\u003C\/ul\u003E\u003Cspan class=\u0022highwire-journal-article-marker-end\u0022\u003E\u003C\/span\u003E\u003C\/div\u003E\u003Cspan id=\u0022related-urls\u0022\u003E\u003C\/span\u003E\u003C\/div\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/mdc.sagepub.com\/sites\/all\/modules\/highwire\/highwire\/plugins\/highwire_markup_process\/js\/highwire_openurl.js?nzl4c1\u0022\u003E\u003C\/script\u003E\n\u003C\/body\u003E\u003C\/html\u003E"}