Clinical Trial Highlights

• TAVR Decreases Mortality When Compared with Surgery in High-Risk Patients
• SYMPLICITY HTN-3 Trial: No Blood Pressure Reduction in Patients with Resistant Hypertension Treated with Renal Denervation
• Darapladib without Significant CV Benefit in Stable Coronary Heart Disease (STABILITY)
• Monoclonal Antibody Reduces LDL-C in Presence of Statin (LAPLACE-2)
• Higher Rate of Device Success with Balloon-Expandable Transcatheter Aortic Valve (CHOICE)
• PCSK9 Inhibitor Slashes LDL-C in Statin-Intolerant Patients (GAUSS-2)
• Dual PPAR Agonist Fails to Improve CV Outcomes after ACS (AleCardio)
• Early CRT Improves Long-Term Survival in Mild Heart Failure (MADIT-CRT)
• Minimal MI Risk with Undetectable hs-cTnT and No ECG Ischemia in ED Patients with Chest Pain
• Perioperative Aspirin Does Not Reduce Cardiovascular Events in Noncardiac Surgery (POISE-2)
• Perioperative Clonidine Does Not Reduce CV Events in Patients Having Noncardiac Surgery (POISE-2)
• Methylprednisolone Not Beneficial in High-Risk Cardiac Surgery Patients (SIRS)
• Metformin Doses Not Reduce Heart Failure after STEMI in Patients without Diabetes (GIPS-III)
• Bariatric Surgery for Treatment of Type 2 Diabetes in Obese Patients: 3-Year Outcomes (STAMPEDE)
• Single-Center Study Finds Bivalirudin Associated with Increased Ischemic Risk in Primary PCI for STEMI (HEAT PPCI)