PT - JOURNAL ARTICLE AU - Misra-Press, Anita ED - Schuler, Martin TI - LUX-Lung 5 DP - 2015 Jun 19 TA - MD Conference Express PG - 13--14 VI - 15 IP - 8 4099 - http://mdc.sagepub.com/content/15/8/13.short 4100 - http://mdc.sagepub.com/content/15/8/13.full AB - LUX-Lung 5 is the first prospective randomized, phase 3 trial to demonstrate superior progression-free survival by continuing afatinib plus paclitaxel as fourth-line treatment vs single-agent chemotherapy in patients with non–small cell lung cancer who had disease progression on chemotherapy with the combination of erlotinib plus gefitinib and with afatinib monotherapy with a manageable safety profile.