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JOURNAL

Clinical Medicine Insights: Dermatology

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Nicolau Syndrome: A Review of the Literature

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Publication Date: 04 Feb 2010

Type: Review

Journal: Clinical Medicine Insights: Dermatology

Citation: Clinical Medicine Insights: Dermatology 2010:3 1-4

doi: 10.4137/CMD.S3630

Abstract

Nicolau Syndrome, first described in the 1920’s in patients treated with bismuth salts for syphilis, is a rare adverse reaction at the site of intramuscular drug injection. It is clinically characterized by severe pain immediately after injection, and rapid development of blanched skin or livedoid reticular patches. Occlusion of peripheral arterial vessels is suggested to play a major pathogenic role. Since there is no specific therapy for this condition, an appropriate conservative treatment should be applied.


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I highly recommend publication in Libertas Academia journals. The entire submission, review and publication process for our article in Clinical Medicine Insights: Dermatology was easy and quick.  The reviews were very professional and helpful and the publication fees were reasonable.  We also appreciate that our article is available online free of charge to anyone interested in it.
Dr Lisa Roche (New Jersey Department of Health and Senior Services, Trenton, NJ, USA)
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